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From397US$ /night
Check-in
25Feb2026Select date
Check-out
26Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview and Details

9300 S Main Street, Houston, Texas, United States
-
Near the Museum District
Great
8.9
9.3
/10
4.2
4.2
/5

Location

The Holiday Inn Express & Suites Houston S - Medical Ctr Area is conveniently located near Texas Medical Center, just a mile from NRG Stadium and Arena. Guests can utilize the complimentary shuttle service to and from the Medical Center, enhancing ease of travel. Proximity to major attractions like the Museum District and Johnson Space Center makes this location appealing for both leisure and business travelers.

Rooms

Redesigned guestrooms at the hotel include options with one king bed or two queen beds to suit various travel needs. All rooms are equipped with a 43-inch LCD HD TV, microwave, and mini refrigerator, ensuring convenience during stays. High-Speed Internet Access (HSIA) is available in both wired and wireless forms throughout the hotel.

Dining

The hotel serves a complimentary hot breakfast each morning, featuring a variety of popular breakfast items to start the day. Fresh coffee and tea supplies are available in the lobby for guests to enjoy at their leisure. This dining option is included in the stay, adding value to the experience.

Business Facilities

For corporate needs, the hotel includes a Business Center equipped with printers, copiers, and office supplies to facilitate productivity. Meeting space is available, accommodating up to 66 attendees, suitable for various events. This versatile space can be divided, maintaining functional use for smaller groups.

Wellness and Recreation

Guests can enjoy the seasonal outdoor pool, open daily from 10 AM to 10 PM, offering a refreshing escape. A Fitness Center is also available for those wishing to maintain their workout routines during their stay. The fitness area is equipped with treadmills, ellipticals, and free weights.

Highlights

Location: near Texas Medical Center

Rooms: one king bed or two queen beds

Dining: complimentary hot breakfast

Business: meeting space accommodating up to 66 attendees

Must-do experiences

  • Visit the Houston Museum District for world-class exhibitions.
  • Try the brisket at the renowned Hickory Hollow Restaurant.
  • Stroll through the vibrant stalls at Houston's Chinatown.
  • Catch a game at NRG Stadium for an electrifying experience.
  • Explore the beautiful Hermann Park and its serene gardens.
View all

Choose Your Room Category

The hotel offers a range of accommodations including doubles, family rooms, and suites—plus breakfast, free cancellation, and special rates.
Specialty Room
2 persons
Air conditioning
Suite Mobility Access Roll Shower or Non-Smoking
2 persons
1 King-size bed
Shower
Air conditioning
Suite Only Hearing Accessible
2 persons
2 King Size Beds
Air conditioning
King Suite Communication Accessible
2 persons
1 King-size bed and 1 Sofa bed
Air conditioning
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Room Availability and Pricing Calendar

Find available rooms and check today's best prices!

Facilities

This hotel provides premium amenities for a memorable and relaxed stay
Facilities: Perfect
9.1/10Review score

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Outdoor swimming pool

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Hotel Location

9300 S Main Street, Houston, Texas, United States
Map view
9300 S Main Street, Houston, Texas, United States
Nearby
1000 Block South Loop
World Birding Center
1900 ft
Restaurants
Hank's Ice Cream Parlor
100 ft
9291 Main St
Popeyes Louisiana Kitchen
1.1 mi
9120 Main St
Sleepys Po-Boys
1.0 mi
9591 Main St
Five Guys
4900 ft
8505 S. Main Street Unit 380
Panda Express
4900 ft
8505 Main St
Denny's
1.5 mi
3332 S Loop W
Sonic Drive-In
1.1 mi
8504 Main Street
Explore Houston
Explore Houston
Top Attractions
Activities
Dining
Entertainment
NRG Stadium
17 minutes' walk
Home to the Houston Texans, NRG Stadium hosts exciting sports events and concerts year-round.
Houston Zoo
50 minutes' walk
The Houston Zoo features diverse wildlife and engaging exhibits, offering family-friendly fun. Check for free admission days.
Astrodome
20 minutes' walk
A historic landmark, the Astrodome is known as the world's first domed stadium. Great for sports history buffs.
Holocaust Museum Houston
35 minutes' walk
This educational museum offers insights into the Holocaust, with powerful exhibits and survivor stories.
Hermann Park
25 minutes' drive
A beautiful park with walking trails, paddle boats, and picnic spots, perfect for family outings or relaxing walks.
World Birding Center
10 minutes' walk
This center offers unique bird-watching opportunities and educational programs. Ideal for nature lovers.
Yoga Studio
10 minutes' drive
Local yoga studios provide classes for all levels. Great for relaxation after a busy day of exploring.
Six Flags Astroworld
20 minutes' drive
Thrill-seekers can enjoy numerous rides and attractions at this exciting amusement park.
Hank's Ice Cream Parlor
1 minute' walk
A cozy spot for ice cream lovers, featuring a variety of delicious flavors and sundaes.
Popeyes Louisiana Kitchen
25 minutes' walk
Famous for its flavorful fried chicken and biscuits, this casual eatery is a must-try for fast food enthusiasts.
Five Guys
18 minutes' walk
Known for its burgers and fries, this casual dining option offers fresh, customizable meals in a relaxed setting.
Sleepys Po-Boys
20 minutes' walk
Casual eatery serving classic Po-boys, perfect for a quick and tasty meal after a day out.
NRG Park
25 minutes' drive
A vibrant venue hosting various events including concerts and expos, suitable for a fun night out.
Jazz Education
10 minutes' walk
This venue offers live jazz performances and educational programs, promoting local music talent.
Children's Museum of Houston
60 minutes' drive
A family-friendly museum filled with interactive exhibits, perfect for keeping kids entertained.
The Houston Museum of Natural Science
55 minutes' drive
Home to stunning exhibits and a planetarium, ideal for all ages, and definitely a highlight for visitors.
Navigating city
City Centre
Houston15 min  ·  6.0 mi
Airports
William P. Hobby Airport (HOU)33 min  ·  13.7 mi
George Bush Intercontinental Airport - Houston (IAH)64 min  ·  26.2 mi
Train
Reliant Park Station23 min  ·  1.2 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg serves a full breakfast for free. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
47
Former name
holiday inn express & suites houston s - medical ctr area, an ihg hotel

Guest Reviews and Hotel Ratings

Honest Guest Feedback Based on Real Stays
Review score
Based on 446 verified reviews
9.0/10
Perfect
91%
Recommend
Breakfast
7.6/10
Cleanliness
9.3/10
Comfort
9.3/10
Facilities
9.1/10
Free Wi-Fi
8.7/10
Location
9.0/10
Paid Wi-Fi
9.4/10
Staff
9.2/10
Value for money
8.6/10
Pros
Clean rooms
Complimentary breakfast
Friendly staff
Free parking
Well-maintained pool
Cons
Uncomfortable bed
Excessive noise
Guest reviews
based on 554 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
Questions of the users
About Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg
Is there a shuttle service that transports guests to MD Anderson?
10 December 2024
Yes, there is a complimentary shuttle available for rides to and from MD Anderson.
Can the shuttle take guests to Hobby Lobby or the stadium?
15 January 2025
The shuttle does not provide pick-up from Hobby Lobby and does not service the stadium; it only operates between the hotel and Medical Center hospitals.
Are elevators available in the building?
05 February 2025
Yes, the hotel is equipped with elevators for guests.
Is it possible to check in early, and is there a shuttle to NRG Stadium?
28 March 2025
Early check-in may be available for a fee of $50, but the shuttle does not go to NRG Stadium.
Are there any discounts for guests visiting MD Anderson?
20 April 2025
Unfortunately, discounts for visits to MD Anderson are not provided.
What is the minimum age requirement for checking in?
12 May 2025
Guests must be at least 21 years old to check in, accompanied by a valid ID.
Is the hotel smoke-free, or are there designated smoking areas?
30 June 2025
The hotel is a completely non-smoking property, with no smoking rooms available.
Is parking available for guests, and is there a fee?
11 July 2024
Parking is complimentary for all hotel guests.
Are there shuttle services to and from the airports?
22 August 2025
Currently, there are no shuttle services to the airports; the shuttle only services the Medical Center clinics and hospitals.
Do you allow pets, or is the hotel pet-friendly?
14 September 2025
The hotel does not accept pets, but there is a pet resort located approximately 2.9 kilometers away.

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